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The USS Defiant (NX-74205) was a Federation Defiant-class escort ship in service in the late 24th century. The Defiant was a prototype for this new class of 'battleships' originally developed in response to the Borg threat. The Defiant was assigned to Deep Space 9 to increase the threat toward the Dominion. The USS Defiant served as a flagship in the Dominion War until it was destroyed by the Breen in 2375.